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CHANGELOG.md

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Changelog

All notable changes to this project will be documented in this file.

The format is based on Keep a Changelog, and this project adheres to Semantic Versioning.

[1.1.0] - 2024-10-22

Changed

  • Updated GENCODE versions:
    • Human genome updated from Release 46 to Release 47 (GRCh38.p14).
    • Mouse genome updated from Release M35 to Release M36 (GRCm39).

[1.0.0] - 2024-10-03

Added

  • Initial Release of the Genome Reference Builder Snakemake pipeline.
  • Automated genome indexing for:
    • Human: GENCODE Release 46 (GRCh38.p14)
    • Mouse: GENCODE Release M35 (GRCm39)
  • Integration of essential bioinformatics tools:
    • STAR (v2.7.11b)
    • RSEM (v1.3.3)
    • Cell Ranger (v8.0.1)
    • HISAT2 (v2.2.1)
    • Kallisto (v0.51.0)
    • Salmon (v1.10.1)
  • GTF filtering step based on the 10x Genomics filtering scheme to ensure consistency between Bulk RNA-seq and Single-cell RNA-seq analyses.
  • Configuration file (config.yaml) pre-configured with May 2024 GENCODE versions for human and mouse genomes.
  • Support for both direct execution and SLURM job scheduler submission.
  • Comprehensive README.md with detailed instructions on installation, configuration, usage, and troubleshooting.
  • Project structure setup, including directories for configuration, logs, and output.